Staff scientists

Photo of Ting Chen, PhD

Ting Chen, PhD, (tchen12@partners.org) is a joint staff scientist with expertise in performing proof-of-concept studies and co-clinical trials using various lung cancer GEMMs and xenograft models. His current projects in the Jänne Lab involve testing allosteric EGFR inhibitors targeting C797S mutation, TKi against EGFR Ex20ins, and AZD9291 resistance mechanism, among others.

Photo of Chiara Ambrogio, PhD

Chiara Ambrogio, PhD, (Chiara_Ambrogio@dfci.harvard.edu) investigates the KRAS signaling pathway in both normal and pathophysiologic states, to aid in developing new therapeutic strategies. Using isogenic cell lines of mouse and human origin expressing different KRAS oncogenic mutations, she characterizes novel compounds for the direct inhibition of KRAS in lung cancer.